Research

Research Programmes

The Centre has identified following major programmes for research
1. Surveillance and monitoring of important equine diseases including emerging and existing diseases with special emphasis on foal mortality and production losses.
2. Development of effective, affordable and preferably field based diagnostics against major equine diseases threatening equine health and production in India.
3. Development of effective, affordable and potent immunoprophylactics against important equine infectious diseases threatening equines in India.
4. Development of effective plant based products for management of some economically important equine diseases and to enhance performance in equines.
5. To provide diagnostic and consultancy services for beneficiaries particularly equine farmers and breeders.
6. Development of sustainable and economically viable AI technology for mule production in India using cryopreserved jack semen for use at farmers’ door.
7. Development and perfection of artificial insemination techniques in horse production using frozen semen of true to breed indigenous stallions for the consortium of threatening species in India.
8. Breed characterization and in situ conservation of various indigenous breed of horses.
9. Exploiting importance of equine draught power for economically weaker section of the society.
10. Extension activities and Institute Development Programmes for the upgradation of the indigenous breeds of equids in the different parts of the country in collaboration with the State Departments.

Ongoing projects

Equine Health (2010-11) 

Sr.

No.

Title

Team

Date of Start

Date of Completion

1.       

Development of vaccine(s) against equine herpes virus-I infection.

B.K. Singh*, B.R. Gulati and N. Virmani

June, 2003

March,  2010

Extended up to March,  2011

2.        

Development of sensitive and specific diagnostics for Japanese encephalitis in Equines

Baldev R. Gulati*, B.K. Singh, N. Virmani & H.S. Singha

Oct., 2006

March, 2010

Extended up to March,  2011

3.        

Surveillance, Monitoring and Control of Emerging and Existing Diseases of Equines

R.K. Singh*, B.K. Singh, S.K. Khurana, S.C. Yadav, Baldev R. Gulati, Rajender Kumar, P. Malik, Sanjay Kumar, Nitin Virmani, Sanjay Barua, Rajesh Kumar Vaid, A. Arangasamy & Ramesh Dedar

April, 1995

Continuous Service Project

4.        

Cysteine proteinase, a defined antigen of T. evansi for control of trypanosomosis

S.C. Yadav*, Rajender Kumar, Sanjay Kumar & A.K. Gupta

Sept., 2008

Aug., 2010

Extended up to Aug.,  2011

5.        

Genetic and antigenic differentiation of equine influenza viruses

B. K. Singh*, Nitin Virmani, B. C. Bera, B. R. Gulati,
K Shanmugasundaram. & R. K. Singh

Sept., 2009

Aug., 2012

6.        

Development of diagnostics for equine influenza

Nitin Virmani*, Baldev. R.Gulati, Bidhan.C. Bera, B.K.Singh and R.K.Singh

Sept., 2009

Aug., 2012

7.        

Evaluation and Updation of the inactivated equine influenza virus vaccine

R.K. Singh*, Baldev R. Gulati Nitin Virmani, A.K. Gupta and B.K. Singh

Oct., 2009

Sept., 2012

8.        

Diversity of Mx gene and association of polymorphic markers with susceptibility vis-à-vis resistance against Equine Influenza

Balvinder Kumar*, R.C. Sharma, Anju Manuja, R.K. Singh

Sept., 2009

Aug., 2012

9.        

Development of monoclonal antibodies and recombinant antigens based assays for detection of Trypanosoma evansi infection in equines

Rajender Kumar*, S.C. Yadav, Sanjay Kumar and Baldev R. Gulati

Sept. 2010

 

Sept. 2012

10.     

Characterization of Toll-like receptor 9 and its role in CpG immuno-modulation in equines

Anju Manuja*, Balvinder Kumar, Sanjay Kumar, H.S. Singha and R.K. Singh

Oct. 2010

 

Oct. 2013

11.     

Development of recombinant protein-based immune-diagnostic kit for equine infectious anemia (EIA)

R.K. Singh*, Praveen Malik H.S. Singha and Sameer Srivastava

Sept. 2010

 

Aug. 2012

12.     

Development of targeted drug release therapeutics using nanoparticles in Equine Medicine

Anju Manuja*, Neeraj Dilbaghi, Sandeep Kumar, Rajender Kumar, Balvinder Kumar and S.C. Yadav

Oct. 2010

 

Oct. 2013

13.     

Studies on donkey lactoferrin and its therapeutics application

Sanjay Gupta*, AK Gupta, TP Singh, R. Kumar,  Rajesh Vaid, Anju Manuja & RK Singh

Sept 2009

August 2010

Equine Production (2010-11)

Sr. No.

Title

Team

Date of Start

Date of Completion

1.          

Molecular characterization of indigenous breeds of horse for genetic diversity within and between different breeds.

A.K. Gupta* and Anuradha Bhardwaj

Oct., 2006

March 2011

2.          

Characterization of indigenous non-descript and geographically distinct donkeys

A.K. Gupta*, Yash Pal, R.C. Sharma, Anuradha Bhardwaj and Sanjay Kumar

Aug. 2010

July, 2014

3.          

Enhancing reproductive efficiency in horses through semen cryopreservation and embryo transfer technologies

A. Arangasamy*, Thirumala Rao Talluri,Yash Pal and Jitendar Singh

Sep. 2009

Aug. 2011

4.          

 Studies on class I and II genes of Major Histocompatibility Complex in donkeys

R. C. Sharma*, Balvinder Kumar and A. K. Gupta

April 2010

March 2013

5.        

Draughtability studies and utilization of equine (mule and donkey) energy in agricultural operations including transport (AICRP)

Yash Pal*, R A Legha, P A Bala, N. Lal and A K Gupta

April 2009

March 2011

6.        

Cloning Expression and characterization of equine chorionic gonadotropin (eCG)

Anuradha Bhardwaj*, A.K. Gupta, Sanjay Kumar and Varij Nayan

Dec. 2010

Nov. 2013

VTCC (2010-11)

 

Sr. No.

 

Title

Team

Date of Start

Date of Completion

1

Isolation, maintenance and characterization of bacterial pathogens and their molecular identification

Rajesh Kumar Vaid*, Sanjay Barua, Mamta Tigga, Shanmugasundaram & B.C. Bera

June, 2007

May, 2010. Extended up to May 2011

1.                   

Isolation, molecular characterization and reposition of viruses of animal origin

R.K. Singh*, Sanjay Barua, B.C. Bera, R. K. Vaid,
K. Shanmugasundaran and B.R. Gulati

Sep 2009

Aug 2012

The Centre is providing not only consultancy and advisory services to its end users but also takes care about equine health, reproduction, conservation, evaluation and improvement of the equine germ plasm. The technologies developed by the Centre in the areas of equine health, reproduction and production are assessed and refined by testing in the field before these are transferred to the equine owners directly or through the established institutions of State Animal husbandry Departments and other Government agencies, practising veterinarians and equine industry by providing appropriate literature, organization of training courses, publication of information bulletins and organization of seminar, symposia, exhibits and horse show etc.

Consultancy
The Centre provides consultancy and advisory services efficiently and effectively to the beneficiaries in the areas of equine health and production, by providing (i) schedules for vaccination, deworming and other preventive sprays to control arthropod vectors of infectious agents, (ii) package of practices for the production of superior quality mules and donkeys by employing artificial insemination and superior donkey germplasm, and (iii) early pregnancy diagnosis through ultrasonography. The diagnosis, treatment and prevention of infectious and non-infectious disease conditions are being done for the benefit of the poorest of the poors, who cannot afford the cost of equine health care. The Centre has adopted one village near Bikaner in Rajasthan and another village in Hisar district in Haryana to provide the services free of cost to the equine owners by making frequent visits. Adoption of more villages and poor equine owners is underway.

Patents
The Centre has applied for two patents in the field of disease diagnosis. Patent has been granted by the Patent Office, Government of India on application (2199/DEL/96) entitled "A method for preparation of a diagnostic kit useful for forecasting Equine Herpes Virus-1 disease" authored by Rattan et al. This has been notified on October 25, 2003 in the Gazette of India, classified as 55E4 1891278. The patent has been granted both for the process and product.

Another application for complement fixation test (CFT) based diagnostic COFEB-Kit developed by NRCE for the detection of Babesia equi antibodies was filed to the patent office Delhi. Patent application no 36/Del/2001 entitled "Complement fixation test based COFEB-Kit for diagnosis of Babesia equi infection in equines" has been finally submitted after first examination report. A divisional application for patenting of product has also been submitted through ICAR to Patent Office, New Delhi.

Commercialisation of Technology
The services for diagnosis of equine infectious anaemia are being provided to equine industry on payment basis to generate resources. Similarly equine influenza vaccine is also being supplied to equine industry and equine owners on payment basis. The Centre is earning revenue to the tune of Rs.16 lakhs through Contract Service during one year. In order to achieve the targeted goals on given time scale, the infrastructure and capabilities would be updated and linkages will be established for sharing of expertise and technologies and to improve facilities for national and International trainings. Involvement of multi-institutional Faculty will be sought with appropriate collaborations.