Research

Research Programmes

The Centre has identified following major programmes for research
1. Surveillance and monitoring of important equine diseases including emerging and existing diseases with special emphasis on foal mortality and production losses.
2. Development of effective, affordable and preferably field based diagnostics against major equine diseases threatening equine health and production in India.
3. Development of effective, affordable and potent immunoprophylactics against important equine infectious diseases threatening equines in India.
4. Development of effective plant based products for management of some economically important equine diseases and to enhance performance in equines.
5. To provide diagnostic and consultancy services for beneficiaries particularly equine farmers and breeders.
6. Development of sustainable and economically viable AI technology for mule production in India using cryopreserved jack semen for use at farmers' door.
7. Development and perfection of artificial insemination techniques in horse production using frozen semen of true to breed indigenous stallions for the consortium of threatening species in India.
8. Breed characterization and in situ conservation of various indigenous breed of horses.
9. Exploiting importance of equine draught power for economically weaker section of the society.
10. Extension activities and Institute Development Programmes for the upgradation of the indigenous breeds of equids in the different parts of the country in collaboration with the State Departments.

Ongoing projects

                                                                                 ON-GOING RESEARCH PROJECTS (2016-17)

EQUINE HEALTH

Sr. No.

Title

Team

From

To

PIMS Code

1.               

Surveillance, Monitoring and Control of Emerging and Existing Diseases of Equines

S.K. Khurana*,  S.C. Yadav, B.R. Gulati, Rajender Kumar,  Sanjay Kumar, N. Virmani, Sanjay Barua,   Rajesh Vaid,  Ramesh Dedar,  H. Singha, Anju Manuja, Balvinder Kumar and B. N. Tripathi

April, 1995

 

Continuous Service

Project

IXX00257

2.               

Evaluation of in vitro growth inhibitory efficacy of some novel synthetic drug molecules against Theileria equi  haemoprotozoa

Sanjay Kumar*, Rajender Kumar and A. K. Gupta

Nov. 2013

 

March, 2017

IXX10288

3.               

Investigations on Neuropathogenic and  Non -neuropathogenic Variants of Equine Herpes Virus-1 and associated Latency among Equines in India

 B. R. Gualti,* Nitin Virmani and Riyesh T.

Sept. 2013

March, 2017

IXX10275

4.               

Pathology of EHV-1 infection in BALB/c mice post- immunization with glycoprotein (gB, gD & gM) and bacterial artificial chromosome construct of EHV-1

Nitin Virmani*, B. R. Gulati and

B. C. Bera

Oct, 2013

 

March, 2017

IXX10287

5.               

Development of diagnostics for emergency preparedness and monitoring of emerging equine viral diseases

Balvinder Kumar.* H.S. Singha and Anju Manuja

April, 2014

March, 2017

IXX10853

6.               

Nanobased therapeutic interventions against osteoarthritis

Anju Manuja*, Balvinder Kumar and Riyesh T.

April 2016

March 2019

IXX12559

NCVTC

Sr. No.

Title

Team

Duration

To

PIMS Code

1.        

Development of bacteriophage repository

Taruna Anand*, R. K.  Vaid, Sanjay Barua and B.C. Bera

Oct.2013

Oct.2016

IXX10698

2.        

Authentication and accessioning of viruses of animal origin (Service Project)

Sanjay Barua,* Naveen Kumar, B.C. Bera, Riyesh T. and Taruna  Anand

May 2015

Service Project

IXX11882

3.        

Isolation, characterization and Development of repository of poxviruses of caprine, ovine and bovine origin

Sanjay Barua,* Naveen Kumar, B.C. Bera, Riyesh T. and Taruna Anand

May 2015

April 2018

IXX11883

4.        

Phenotypic and genotypic authentication and preservation of network bacterial isolates

R.K. Vaid*, Taruna Anand, B.C. Bera and Riyesh T.

June, 2015

May, 2018

IXX11884

5.        

Prevalence studies for porcine respiratory viruses and development of their repository

B.C. Bera,*, Sanjay Barua, Taruna Anand and Nitin Virmani

January 2016

Dec., 2018

IXX12436

EQUINE PRODUCTION CAMPUS

Sr.

No.

Title

Team

Date of Start

Date of Completion

PIMS Code

1.             

Endocrine, biochemical and gene expression profiling of reproductive states in Marwari Mares

Vijay Kumar*, Sanjay Kr. Ravi, R.K. Dedar and Raghvendra Singh

Oct., 2012

Sept. 2016

IXX09663

2.             

Evaluation of total mixed rations for maintenance horses

P.A. Bala*, R.K. Dedar and N.V. Patil

March 2014

Feb. 2017

IXX11646

3.             

Cryopreservation of semen, artificial insemination and pregnancy diagnosis in equines (service project)

S.K. Ravi*, T.R. Talluri, J. Singh, R.A. Legha, Yash Pal and A.K. Gupta

April, 2015

March, 2018

IXX11844

4.             

Optimization of interspecies somatic cell nuclear transfer technique for production of horse (Equus caballus) cloned embryos

NRCE: T.R. Talluri*, Sanjay Kumar Ravi and Taruna Anand

CIRB: Naresh Seloker*, Dharmendra Kumar and P S Yadav

Nov. 2015

Feb., 2018

 IXX12608

5.             

Characterization of donkey milk with emphasis on important milk proteins

Yash Pal*, R. A. Legha, Anuradha Bhardwaj Sanjay Kumar & A. K. Mohanty

Oct. 2012

Sept., 2016

IXX07761

6.             

Development of rapid diagnostic test for pregnancy diagnosis in horse mares

A.K. Gupta*, Yash Pal, Sanjay Kumar and Sanjay Kr. Ravi

Jan. 2015

June 2017

IXX11645

7.             

Genetic characterization of Marwari horses for selection of true to breed animals

Anuradha Bhardwaj*, A.K.Gupta, Yash Pal, Mamta Chauhan and Vijay Kumar

July 2015

June 2018  

IXX12220

8.             

Development of DNA typing facility for parentage testing in horses.

Mamta Chauhan* Anuradha Bhardwaj, Yash Pal, B.N. Tripathi and A.K. Gupta

Oct. 2015

March 2017

IXX12431

9.             

Assessment of risk factors of equine laminitis and colic

Ramesh Kumar Dedar*, P.A. Bala, Sakar Palecha (RAJUVAS)

Sept. 2016

August 2019

IXX12693

EXTERNALLY FUNDED/INTER-INSTITUTIONAL ON-GOING RESEARCH PROJECTS (2016-17) 

Sr. No.

Title

Name of PI

Date of Start

Date of Completion

PIMS No.

1.       

National Fellow Scheme-Development of sensitive and specific diagnostic assays for detection of Trypanosoma evansi infection in animals using modern molecular tools

Rajender Kumar*

April,  2011

April, 2019

OXX01431

2.       

All India Coordinated Research Project on Utilization of Animal Energy with enhanced system efficiency (AICRP on UAE)

R A Legha, Yash Pal (upto 4th Jan., 2015) and Vijay Kumar (from 5th Jan. 2015)

July, 2009

March, 2017

OXX00486

3.       

Characterization of donkeys of Rajasthan Network Project from NBAGR, Karnal

Yash Pal*, A.K. Gupta and R.K. Dedar

April, 2014

Sept., 2016

OXX02851

4.       

DBT-NER Centre for Advanced Animal Diagnostics and Services on Animal Health and Diseases (ADSAHD)

B.N. Tripathi*, Sanjay Barua, Nitin Virmani, S.C. Yadav, B.R. Gulati, Rajender Kumar, R.K. Vaid, B.C. Bera, Taruna Anand & Riyesh T.

Sept., 2013

April, 2019

OXX02933

5.       

All India Network Programme on Neonatal Mortality in Farm Animals

Sanjay Kumar*, Ramesh Dedar, B.R. Gulati, Nitin Virmani and S.K. Khurana

Jan., 2015

March, 2017

OXX03934

6.       

CRP on Vaccines and Diagnostics

B.R. Gulati*,

Component-I (B.R. Gulati& Nitin Virmani)

Component-II (Nitin Virmani, B. R. Gulati & B.C. Bera)

Component-III (Sanjay Kumar & Rajender Kumar)

May, 2015

March, 2017

OXX03182

7.       

CRP on Agrobiodiversity (Sub Project 6 Management of NCVTC)

Sanjay Barua*, R.K. Vaid, Naveen Kumar, Taruna Anand, B.C. Bera, Riyesh T.

August, 2015

July, 2017

OXX03183

8.       

Targetting a host cell protein kinase for development of antiviral therapeutics against PPR virus

Naveen Kumar* and Sanjay Barua

August, 2015

March, 2018

OXX03186

9.       

Generation of reverse genetics based equine influenza virus and explore its potential as vaccine candidate through challenge studies in mice model

At NRCE: Nitin Virmani, Principal Scientist, Veterinary Pathology  & At NIHSAD, Bhopal: Dr. Sandeep Bhatia, National Fellow & PS

Collaborators (Name, Designation and Specialization)Richa Sood, Sr. Scientist, NIHSAD, BhopalB. C. Bera, Scientist, NRCE, Hisar

April, 2015

March, 2018

IXX12259

10.   

Pathogenecity and immunogenicity of recombinant neurogenic and non-neurogenic mutant equine herpesvirus-1 (in tissue explants and murine model) and their potential as vaccine candidate(s)

Nitin Virmani*

Jan., 2016

March, 2017

OXX03412

11.   

Feasibility studies on biogas and compost production from mule dung in hilly regions in India

B.N. Tripathi*, R.K. Vaid and R.A. Legha

Nov., 2015

March, 2017

OXX03413

12.   

Validation study of a western blot (WB) technique and ELISAs for serological diagnosis of glanders in equids for the purpose of certifying freedom from infection in individual animals for trade or movement

H.S. Singha*

Dec., 2015

March, 2017

OXX03410

13.   

Generation of induced pluripotent stem (iPS) cells from buffalo fetal fibroblasts through non-viral approaches

Dharmendra Kumar (CIRB)*, Naresh Lalaji Selokar, P.S. Yadav and Taruna Anand (NCVTC, NRCE)

Feb., 2016

July, 2017

OXX03592

(CIRB)

 

The Centre is providing not only consultancy and advisory services to its end users but also takes care about equine health, reproduction, conservation, evaluation and improvement of the equine germ plasm. The technologies developed by the Centre in the areas of equine health, reproduction and production are assessed and refined by testing in the field before these are transferred to the equine owners directly or through the established institutions of State Animal husbandry Departments and other Government agencies, practising veterinarians and equine industry by providing appropriate literature, organization of training courses, publication of information bulletins and organization of seminar, symposia, exhibits and horse show etc.

Consultancy
The Centre provides consultancy and advisory services efficiently and effectively to the beneficiaries in the areas of equine health and production, by providing (i) schedules for vaccination, deworming and other preventive sprays to control arthropod vectors of infectious agents, (ii) package of practices for the production of superior quality mules and donkeys by employing artificial insemination and superior donkey germplasm, and (iii) early pregnancy diagnosis through ultrasonography. The diagnosis, treatment and prevention of infectious and non-infectious disease conditions are being done for the benefit of the poorest of the poors, who cannot afford the cost of equine health care. The Centre has adopted one village near Bikaner in Rajasthan and another village in Hisar district in Haryana to provide the services free of cost to the equine owners by making frequent visits. Adoption of more villages and poor equine owners is underway.

Patents
The Centre has applied for two patents in the field of disease diagnosis. Patent has been granted by the Patent Office, Government of India on application (2199/DEL/96) entitled "A method for preparation of a diagnostic kit useful for forecasting Equine Herpes Virus-1 disease" authored by Rattan et al. This has been notified on October 25, 2003 in the Gazette of India, classified as 55E4 1891278. The patent has been granted both for the process and product.

Another application for complement fixation test (CFT) based diagnostic COFEB-Kit developed by NRCE for the detection of Babesia equi antibodies was filed to the patent office Delhi. Patent application no 36/Del/2001 entitled "Complement fixation test based COFEB-Kit for diagnosis of Babesia equi infection in equines" has been finally submitted after first examination report. A divisional application for patenting of product has also been submitted through ICAR to Patent Office, New Delhi.

Commercialisation of Technology
The services for diagnosis of equine infectious anaemia are being provided to equine industry on payment basis to generate resources. Similarly equine influenza vaccine is also being supplied to equine industry and equine owners on payment basis. The Centre is earning revenue to the tune of Rs.16 lakhs through Contract Service during one year. In order to achieve the targeted goals on given time scale, the infrastructure and capabilities would be updated and linkages will be established for sharing of expertise and technologies and to improve facilities for national and International trainings. Involvement of multi-institutional Faculty will be sought with appropriate collaborations.